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The Detect test differs from the antibody and antigen versions being developed by other companies. Ultimately, for Rothberg, its all about benefiting those he loves, and helping the less fortunate. in chemical engineering from Carnegie Mellon University and an M.S., M.Phil, and Ph.D. in biology from Yale University. It agitates me that we messed up so badly, he said. With each passing week, the situation had grown increasingly dire. As Elana Rothberg was treading in the Arctic Ocean off a Norwegian glacier last summer, a drysuit and sweats staving off the cold, she wondered what could be living in the water around her. In late March, President Trump had proclaimed that the approval of the countrys first rapid-test kits, developed by Abbott Laboratories for use with their I.D. That same daughter, now grown, uses the lab for her own scientific research. What kinds of space are we willing to. content: ; During COVID, theres been an explosion of telemedicine, Rothberg said. But Elana and the intern, Yale student Stephen Wang, are energized about the possibilities. He was sanguine enough about his test that he used the prototypes more than eleven hundred times on his boat in eleven weeks: his family and the crew were screened every day, and he sent drones to shore to ferry samples from prospective visitors. "Jonathan M. Rothberg wants to do for DNA sequencing what Steve Jobs did for computing spread it to the masses. He brought an empty bottle, which he filled with water from a swamp. A fusion of semiconductors, artificial intelligence, and cloud technology has made it possible to create a ubiquitous imaging solution that is clinically significant and category defining. Prior to Xiaomi, Hugo was the Vice President for Android product management at Google, where he led the product team in developing the Android operating system, developer ecosystem and hardware alliances. They hope the strands of DNA will offer leads for potential medical therapies, or other scientific discoveries, just as mapping human genomes has done over the past decade. [8] The idea for 454 Life Sciences came when Noah, his second child, was born in 1999, and had to be sent to the neonatal intensive care unit because of breathing troubles. But there is one thing even more prolific than microbes: the viruses that replicate inside of them. Prior to 454 Life Sciences, Dr. Rothberg founded and served as Chairman and Chief Executive Officer of CuraGen Corporation from 1993 to 2004. I liked having a nucleic-acid test before I brought someone onto my boat, for example, where the attack rate wouldve been horrible.. These can be quick and inexpensive but arent generally as accurate as molecular tests, which indicate not the presence of a viral proxy, like a protein, but of the virus itself. Jonathan Rothberg - Contact For the time being, the university would be relying on a testing program set up by the Broad Institute, in Cambridge, to support institutions in the area. was open to innovative measures, but his team told him that miniature heaters were cheap enough to manufacture that it wasnt worth a regulatory provocation. Gene Machine Yacht Owner Jonathan Rothberg Blends Fun & Science Onboard would grant his test an emergency approval by June. In university labs, small startups, and large life-sciences companies, researchers improvised, drawing upon a variety of techniques to compensate for the lack of national leadership. For instance, in 2017 while the yacht was in . Still, our pediatrician categorically recommended a lab test over a rapid one, the accuracy of which, in the wake of the N.Y.U. He lifted his clunky black wraparound sunglasses up and to the side, rested them askance on the frames of his prescription pair, and gestured to his marine habitat. Our companies NYSE: BFLY NASDAQ: HYPR NASDAQ: QSI Butterfly iQ is a registered trademark of Butterfly Network, Inc. 2023 Blue Cross Blue Shield Association - All Rights Reserved. Elsewhere, it was understood that closure was a real possibility unless help arrived soon. His optimism was, according to his employees, characteristic; Owen Kaye-Kauderer, a co-founder of Homodeus and one of the many bright, industrious twentysomethings with whom Rothberg regularly collaborates, told me that Rothbergs ideal company featured one domain expert surrounded by seven kids who dont know that what theyre trying to do cant be done. At the same time, Rothbergs suspicion that by the beginning of the summer there would still be an urgent need for his intervention betrayed a realism, even a pessimism, about the likelihood of a competent centralized response. study, she did not trust. Rothberg is a tall, lanky, guilelessly charismatic man with a broad, wind-chapped face and a boyish mop of windblown brown hair. 454 Life Sciences and the Baylor College of Medicine Genome Center were the first to complete and make public the sequence of an individual human genome (James D. Watson[9][10]). Dr. Rothberg received his Ph.D., M.Phil., and M.S. And, as he told his investors, their product had long-term post-pandemic potential: what he first called COVID Detect was quickly reimagined as Detect, a flexible diagnostic platform that could easily be retooled to identify cases of the flu, respiratory syncytial virus, and a variety of other maladies. Moreover, the enzymes they needed were made by only about ten suitable venders in the world, and if a small company could even place an order the quotes came in high. [2], Rothberg established a startup accelerator called 4Catalyzer in Guilford, CT, in the early 2010s. His net worth has been growing significantly in 2020-2021. jonathan rothberg daughter - masar.group Detect is one of seven companies founded by Jonathan Rothberg, a scientist, entrepreneur and New Haven native who earned his his Ph.D. at Yale and spearheads the startup accelerator 4Catalyzer. [2], In 2000, 454 Life Sciences was founded as a subsidiary of CuraGen; Rothberg was the CEO of CuraGen at the time. Rothberg has come, over time, to recognize his own administrative shortcomings, and for the COVID-19 project he hired some proven mercenaries for help. Your browser is antiquated and no longer supported on this website. Jonathan Rothberg on what motivates his research His father, Henry Rothberg, had made a small fortune with the invention of a breakthrough form of adhesive for the installation of ceramic tile and stone. Hed assumed that the people in charge would get their act together before long, but he swore to himself that he would face the next pandemic with a simple diagnostic platform of his own devising. Large research universities had the expertise, equipment, and authorization to do their own lab work. His portable MRI sells for fifty thousand dollars, his home ultrasound for two thousand. (A subsequent study, conducted by independent researchers at N.Y.U., indicated an accuracy of barely fifty per cent. Moreover, as Rothbergs wife told him over video chat, there was no way users would give themselves what felt like cranial defilements. Dr. Rothberg previously founded and served as Chairman, Chief Executive Officer, and Chief Technology Officer of Ion Torrent Systems, Inc. from 2007 to 2010, and founded and served as Chairman and Chief Executive Officer of RainDance Technologies, Inc. from 2004 to 2009. Kaye-Kauderer told me that Rothbergs instructions to his team were no pipetting, no nasopharyngeal swabs, no refrigerated enzymes, no liquid transferwe had to keep the whole thing hermetically sealed, end to end. Christopher Mason, a geneticist at Weill Cornell, in New York, and a member of Homodeuss scientific advisory board, told me that such one-pot solutions are trickyother scientists, he said, have tried and failed. He earned a B.S. Detect founder Dr. Jonathan Rothberg has a strong track record of building successful companies that solve important scientific challenges. For use by qualified and trained healthcare practitioners. Fortunately, the ship had been outfitted with Rothbergs demiurgic propensities in mind. Dr. Rothberg is the founder of the 4Catalyzer medical technology incubator and the founder and Chairman of its companies: Butterfly, AI Therapeutics, Inc. (formerly LAM Therapeutics, Inc.), Quantum-Si Incorporated, Hyperfine Research, Inc., Tesseract Health, Inc., Liminal Sciences, Inc. (formerly EpilepsyCo Inc.), Homodeus Inc. and 4Bionics LLC. Husband and wife had to isolate from each other, not only because of her job, but because their daughter has a rare genetic disorder and needs to take immunosuppressive medication. had come around to this way of thinking. For my first invention, fast-DNA sequencing, my son was not breathing. One of these tech companies is called the Butterfly Network, whose mission is to democratize healthcare by making medical imaging accessible to everyone around the world. Thats no easy task. How vials of frozen, genetically engineered rodentsperm, raced to a remote lab in Maine, produced a breed of critters that could help scientists find a treatment or a vaccine. This method could bring the cost of each test down to perhaps three or four dollars. In 2008, Rothberg and a research team used his technique to map and publish the first complete genome of a single individual, the geneticist James Watson. See also our Career page. Butterfly iQ is portable and works anywhere in the world with a cell phone. Other countries rose to the occasion, and were able to use widespread PCR testing to track and manage their outbreaks. The inventor and entrepreneur prophesies a future in which self-testing has become one more morning ritual between brushing our teeth and putting on a pot of coffee. One of his latest companies, Butterfly Network, recently began. So the Butterfly Network invented a whole body, hand-held ultrasound scanner called the Butterfly iQ. [3] Noah turned out to be fine, but Rothberg was frustrated that doctors did not have a rapid test to ensure his son did not have an inherited disease. While quarantining aboard his yacht, Rothberg has devoted himself to developing a diagnostic that is as fast, simple, and inexpensive as a home pregnancy test. He previously served as Chairman of Butterflys board of directors from March 2014 to February 2021, Butterflys Chief Executive Officer from March 2014 to April 2020, and Butterflys President from March 2014 to April 2014. Solutions of greater promise lay on the distant horizon. Jonathan Rothberg a pioneer in genetic sequencing technology, serial entrepreneur, Yale alumnus, and New Haven native will receive the National Medal of Technology and Innovation, the White House announced Dec. 22. . All supplies coming on board were cleaned, and anyone entering the ship had to isolate and test for COVID-19. This summer, they launched the research project by collecting samples from 32 bodies of water across the world. Thats the same tactic Rothberg used years earlier when he invented a device to carry out modern, high-speed DNA sequencing at his former company Ion Torrent, which sold for $725 million in 2010. All prices reflected in USD. With the yacht moored, he hiked three miles into the French islands rocky interior. Rothberg felt compelled to help with the pandemic response. Rothbergs predictions were almost immediately confirmed: a small Massachusetts startup, E25Bio, soon announced that they had raised millions of dollars of venture capital, and anticipated approval for their fifteen-minute at-home antigen test within two months. Lets let people see their families for the holiday. The pessimism was taken for granted: if people like him werent going to save you, who would? American scientist and entrepreneur (born 1963), National Medal of Technology and Innovation, "Laurencin and Rothberg Receive White House Honors", "Rothberg Seeks to Make DNA Sequencing Common", "On board with Jonathan Rothberg, owner of 55m explorer yacht Gene Machine", "Quantum-Si taps founder Rothberg, prolific medtech entrepreneur, as interim CEO", "Curagen Form 10-K for the fiscal year ended December 31, 2000", Project Jim: Watsons Personal Genome Goes Public, "Roche to close 454 Life Sciences as it reduces gene sequencing focus", "RainDance Technologies To Be Sold to Bio-Rad", "Guilford incubator 4Catalyzer aims for game-changing medical products", "An Entrepreneur Aims To Peer Inside The Body With A Small, Simple, Cheap Device", "Aiming To Revolutionize Medical Ultrasound, Butterfly Raises $250 Million At A $1.25 Billion Valuation", "Investor Relations - Quantum-Si Incorporated", "Quantum-Si closes USD1bn+ SPAC deal with HighCape", "A serial entrepreneur wants his portable MRI to transform medicine", "Hyperfine's portable MRI nets FDA clearance for deep-learning-powered imaging", "Hyperfine Announces Receipt of Additional $3.3 Million Grant to Improve Access to Neonatal and Pediatric Brain Imaging in Low-Resource Settings Globally", "Hyperfine, Liminal to go public in $580M SPAC deal", "Detect Combines Lab-Quality Covid Testing with At-Home Convenience", "Detect CEO Hugo Barra on how its Covid test differs from a rapid antigen test", "On April 15, 2009, the D2OL distributed computing project will officially end operations", "Alumnus Rothberg enlists students to solve next healthcare challenges", "Graduate School Honors Four Alumni with Wilbur Cross Medals | Yale Graduate School of Arts & Sciences", https://en.wikipedia.org/w/index.php?title=Jonathan_Rothberg&oldid=1142428350, Members of the United States National Academy of Engineering, Carnegie Mellon University College of Engineering alumni, Short description is different from Wikidata, Articles with unsourced statements from March 2023, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2023, at 09:20.
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